Clinical Value of Pregnanediol Assays

The value of complement assays in clinical chemistry.

Comparison of methods for pregnanediol determination.

A gas chromatographic method of pregnanediol determination has been carried out on 24-hr. urine specimens collected during various phases of the menstrual cycle and during pregnancy. Pregnanediol values were correlated with endometrial histology and cycle day in nonpregnant subjects, and with duration of gestation during pregnancy. Determinations were performed on free pregnanediol and on the a...

Excretion of Sodium Pregnanediol Glucuronidate

Venning and Browne (1 to 7) have shown that sodium pregnanediol glucuronidate is excreted in urine of human pregnancy in concentrations which become increasingly higher as gestation approaches term. Although this demonstration has been repeatedly confirmed (8 to 16), relatively few workers have studied the precise levels and ranges of normal excretion, or have secured long-continued records of ...

Clinical Application of Fibrinolytic Assays

Standardization of clinical enzyme assays.

During 1969, discussions between the Standards Subcommittee of the Laboratory Equipment and Methods Advisory Group of the Department of Health and Social Security and representatives of professional societies concerned with the assay of enzymes for diagnostic purposes led to the establishment of a working party to consider the current state of accuracy and reliability of diagnostic enzymology a...